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News

Seminars and Events

  • Apr
    5

    Clinical examination of ocular diseases relies upon a battery of tests to reveal structural and functional losses. In some cases, there may be discordance between structural and functional measurements. A classic example is pre-perimetric glaucoma, in which overt structural losses are apparent in the absence of clinically detectable functional deficits. Discordance between techniques can also manifest as differences in the magnitude of loss detected using various perimetric methods, such as static and kinetic perimetry. Tests of structure and function are important, so is there a way to reconcile the discordance apparent between them? This presentation will outline some of the methods established by our laboratory working towards reconciling discordance between clinical techniques, and their application for assessment of ocular diseases.

  • Apr
    18

    From the emergence of the internet, to predatory publishers, the world of academic publishing has experienced enormous pressure to grow and evolve over the past 20 years. Scholars must now navigate a more complex landscape with new traps and tricks for the unwary. This presentation will discuss some of the forces that are shaping academic publishing and explore where we may be heading and why. 

Research Spotlight

Keratoconus (KC) is a relatively common disease of the cornea, the clear curved part at the front of the eye needed for good vision. KC leads to loss of corneal transparency, thinning and shape changes that affect vision and quality of life. Why the cornea degenerates in KC is complex but involves environmental and genetic factors. To help identify candidate genes critical in KC we analysed global gene expression. Two novel genes (Notch1 and PLLP) were decreased in KC - these genes affect the normal way corneal cells grow and migrate, and signal to each other. We will now study the function of these genes in human corneas to assess their r...

Vision relies on the exchange of information between the eye and the brain through a million nerve fibres forming the optic nerve. This makes the optic nerve head, the exit point of these fibres from the eye, arguably the most important structure to assess eye health. The increasing number of methods available to visualise this structure in the back of the eye, however, can be confusing for patients and clinicians alike.