Daniel Tilia

PhD Candidate

PhD Candidate

Research Title: Associations between binocular vision disorders and contact lens dissatisfaction 

Supervisors: Professor Eric Papas, Dr Ravi Bakaraju, Dr Lisa Asper 

Email: daniel.tilia@unsw.edu.au

LinkedIn: https://www.linkedin.com/in/daniel-tilia-2193a012/

 

Associations between binocular vision disorders and contact lens dissatisfaction

Daniel Tilia (Student Number: z8629137)

Joint Supervisors: Professor Eric Papas and Dr Ravi C Bakaraju

Co-supervisor: Dr Lisa Asper

This research project aims to:

  1. Assess the extent and level of dissatisfaction among myopic, pre-presbyopic adult contact lens (CL) wearers caused by CL discomfort and binocular vision disorders (BVDs).
  2. Determine the relative efficacy of different CL designs when worn by those with a BVD in terms of subjective and clinical measures.
  3. Explore possible CL designs which may reduce CL dissatisfaction due to a BVD.

While CL discomfort is a well-known cause of CL dissatisfaction, the effect of BVD symptoms is unknown. To date, there are no suitable questionnaires which assess CL dissatisfaction caused by CL discomfort and/or BVD symptoms.

Previous work has identified three questionnaires which may be suitable: Ocular Surface Disease Index (OSDI), Contact Lens Impact on Quality-of-life (CLIQ) and Ranked Symptoms Scale (RSS). These questionnaires were assessed in a clinical trial with a cohort of non-presbyopic, adult CL wearers.

Participants completed the Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) to assess CL discomfort and the Convergence Insufficiency Syndrome Survey (CISS) to assess BVD symptoms. A comprehensive, binocular vision assessment, classified participants as either having BVD or normal. Participants completed the OSDI, CLIQ and RSS after the assessment.

Sixty-five participants have been assessed, and 22% (n=14) were classified with BVDs. The BVD group scored the CISS and the OSDI significantly higher than normals (p=0.006 and p=0.003, respectively), with the vision subscale of the OSDI driving the differences between groups (p<0.001). There were no significant differences between groups for the CLIQ or RSS (p ≥0.099). There were also no significant differences between groups for the OSDI subscales of ocular symptoms and environmental triggers and CLDEQ-8 (p≥0.099), suggesting dissatisfaction due to a BVD is distinct from dissatisfaction due to CL discomfort.

The current clinical trial establishes that a cohort of CL wearers have both a BVD and CL dissatisfaction. The next stage is to perform a clinical trial to determine whether dissatisfaction symptoms (as measured by the OSDI) can be reduced with different CL designs.

The last stage is to use the learnings from the previous two trials to try and design CLs which target BVDs in general, or specific BVDs.

 

BIOGRAPHY  

Daniel Tilia is the Clinical Research Manager at the Brien Holden Vision Institute Limited. He spent 16 years in private practice before joining the Brien Holden Institute in 2006. He has also been a clinical supervisor at the School of Optometry and Vision Science, UNSW since 1994. He has presented at the American Academy of Optometry (AAO), Association for Research in Vision and Ophthalmology (ARVO) and the British Contact Lens Association (BCLA), and as an invited speaker at optometric conferences in Beirut, Hyderabad, Hong Kong, Manila and Singapore. 

Education 

2015 - PhD, UNSW 

2010 - 2012 Graduate Certificate of Ocular Therapeutics, UNSW  

1995 - 1999 Master of Optometry, UNSW 

1986 - 1989 Bachelor of Optometry, UNSW 

RECENT PUBLICATIONS 

Journal Articles 

  1. Sankaridurg P, Bakaraju RC, Naduvilath T, Chen, X, Weng R, Tilia D, et al. Myopia Control with Novel Central and Peripheral Plus Contact Lenses and Extended Depth of Focus Contact Lenses: 2 Year Results from a Randomised Clinical Trial. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 2019. 

  2. Jong M, Tilia D, Sha J, et al. The Relationship between Visual Acuity, Subjective Vision, and Willingness to Purchase Simultaneous-Image Contact Lenses. Optometry and vision science : official publication of the American Academy of Optometry 2019;96:283-90. 

  3. Tilia D, Sha J, Thomas V, Bakaraju RC. Vision Performance and Accommodative/Binocular Function in Children Wearing Prototype Extended Depth-of-Focus Contact Lenses. Eye & contact lens 2018. 

  4. Sha J, Tilia D, Kho D, et al. Comparison of Extended Depth-of-Focus Prototype Contact Lenses with the 1-Day Acuvue Moist Multifocal after One Week of Wear. Eye & contact lens 2018;44 Suppl 2:S157-s63. 

  5. Sha J, Tilia D, Kho D, et al. Visual Performance of Daily-Disposable Multifocal Soft Contact Lenses: A Randomized, Double-Blind Clinical Trial. Optometry and vision science : official publication of the American Academy of Optometry 2018;95:1096-104. 

  6. Sha J, Tilia D, Diec J, et al. Visual Performance of Myopia Control Soft Contact Lenses in Non-Presbyopic Myopes. Clinical optometry 2018;10:75-86. 

  7. Kho D, Fedtke C, Tilia D, et al. Effects of Relative Negative Spherical Aberration in Single Vision Contact Lens Visual Performance. Clinical optometry 2018;10:9-17. 

  8. Diec J, Tilia D, Thomas V, Bakaraju RC. Predicting Short-Term Subjective Vision Performance of Contact Lenses Used in Myopia Control. Eye & contact lens 2018;44:308-15. 

  9. Diec J, Tilia D, Thomas V. Comparison of Silicone Hydrogel and Hydrogel Daily Disposable Contact Lenses. Eye & contact lens 2018;44 Suppl 1:S167-s72. 

  10. Diec J, Naduvilath T, Tilia D. Subjective Ratings and Satisfaction in Contact Lens Wear. Optometry and vision science : official publication of the American Academy of Optometry 2018;95:256-63. 

  11. Bakaraju RC, Tilia D, Sha J, et al. Extended Depth of Focus Contact Lenses Vs. Two Commercial Multifocals: Part 2. Visual Performance after 1 Week of Lens Wear. Journal of optometry 2018;11:21-32. 

  12. Tilia D, Munro A, Chung J, et al. Short-Term Comparison between Extended Depth-of-Focus Prototype Contact Lenses and a Commercially-Available Center-near Multifocal. Journal of optometry 2017;10:14-25. 

  13. Diec J, Tilia D, Naduvilath T, Bakaraju RC. Predicting Short-Term Performance of Multifocal Contact Lenses. Eye & contact lens 2017;43:340-5. 

  14. Diec J, Naduvilath T, Tilia D, et al. Discrimination of Subjective Responses between Contact Lenses with a Novel Questionnaire. Contact lens & anterior eye : the journal of the British Contact Lens Association 2017;40:367-81. 

  15. Tilia D, Bakaraju RC, Chung J, et al. Short-Term Visual Performance of Novel Extended Depth-of-Focus Contact Lenses. Optometry and vision science : official publication of the American Academy of Optometry 2016;93:435-44. 

  16. Sha J, Bakaraju RC, Tilia D, et al. Short-Term Visual Performance of Soft Multifocal Contact Lenses for Presbyopia. Arquivos brasileiros de oftalmologia 2016;79:73-7. 

  17. Papas E, Tilia D, McNally J, de la Jara PL. Ocular Discomfort Responses after Short Periods of Contact Lens Wear. Optometry and vision science : official publication of the American Academy of Optometry 2015;92:665-70. 

  18. Tilia D, Lazon de la Jara P, Zhu H, et al. The Effect of Compliance on Contact Lens Case Contamination. Optometry and vision science : official publication of the American Academy of Optometry 2014;91:262-71. 

  19. Tilia D, Lazon de la Jara P, Weng R, et al. Short-Term Clinical Comparison of Two Dual-Disinfection Multipurpose Disinfecting Solutions. Eye & contact lens 2014;40:7-11. 

CONFERENCE ATTENDANCE 

Daniel Tilia, Ravi Bakaraju, Lisa Asper, Eric Papas. Binocular vision disorders and contact lens dissatisfaction. Association for Research in Vision and Ophthalmology (ARVO), Vancouver, May 2019 

Daniel Tilia; Jennifer Sha; Nisha Yeotikar, Hamdy Amziral, Monica Jong, Jennie Diec; Varghese Thomas; Ravi Bakaraju. Visual performance, accommodative function and digital eye strain with Digital Zone Optics contact lenses. American Academy of Optometry (AAO) San Antonio, November 2018 

Daniel Tilia; Jennifer Sha; Jennie Diec; Monica Jong; Nisha Yeotikar; Varghese Thomas; Ravi Bakaraju. Visual performance and accommodative function with prototype extended depth-of-focus lenses against single-vision contact lenses. ARVO, Honolulu, May 2018  

D. Tilia, J. Sha, J. Diec, M. Jong, N. Yeotikar, V. Thomas, R.C. Bakaraju. Visual performance of prototype extended depth-of-focus contact lenses against single-vision contact lenses in non-presbyopes, AAO, Chicago, October 2017 

D. Tilia, J. Sha, D. Kho, A. Munro, S. Delaney, V. Thomas, K. Ehrmann, R.C. Bakaraju. Accommodative responses in myopic children wearing extended depth of focus contact lenses, ARVO, Seattle, May 2016 

D. Tilia, R.C. Bakaraju, J. Chung, J. Sha, S. Delaney, A. Munro, V. Thomas, K. Ehrmann, B. Holden. Evaluation of novel-design Extended Depth of Focus multifocal contact lenses. British Contact Lens Association (BCLA) Liverpool, May 2015  

D. Tilia, B. Holden, P. Lazon de la Jara, T. Naduvilath. Is contact lens comfort influenced by case contamination? AAO, Denver, November 2014  

AFFILIATIONS AND MEMBERSHIPS 

Fellow of the British Contact Lens Association 

Fellow of the American Academy of Optometry 

Member of the Cornea and Contact Lens Society of Australia  

Member of Optometry Australia  

Member of the Association for Research in Vision and Ophthalmology