Ingrid Ornella Mekountchou Koumbo

PhD Candidate

PhD Candidate

Research Title: Development of an eye model to screen optical interventions for their ability to slow myopia progression 

Supervisors: Associate Professor Klaus Ehrmann, Professor Padmaja Sankaridurg, Dr Fabian Conrad 

Title of the project: Development of an eye model to screen optical interventions for their ability to control myopia progression

Background: Increasing levels of myopia are associated with increased risk of developing visual impairment and blinding complications. To reduce the burden associated with myopia, various interventions to retard the progression of myopia in children have been tried. Some of these interventions show promise and studies are underway to improve the efficacy obtained from these interventions. However, these interventions require long term and expensive clinical studies and therefore limit the ability to measure the efficacy of various interventions. Previous studies have found choroidal thickness to change in response to optical defocus and therefore provide an avenue to screen and select optical interventions based on their ability to elicit the appropriate ocular response prior to conducting long-term clinical studies with such interventions. However, previous studies were mostly confined to central retina and limited to studying choroidal response.

Rationale: It would be highly desirable to be able to screen optical interventions for their ability to elicit the appropriate ocular response over a short period. Candidate interventions that pass the screening test could be further evaluated in long-term clinical trials thus minimising the risk of negative result in a long-term clinical trial.

Aim:

- To determine changes if any in eye length and choroidal thickness at central retina and at various locations along the peripheral retina in response to optical defocus; and

- To develop an eye model based on central and/or peripheral eye length and choroidal thickness that can be used to predict the effect of optical interventions for control of myopia.

Hypothesis:

-No Changes in central and peripheral eye length and choroidal thickness can be measured in response to optical defocus.

-An eye model can be developed to predict the effect of optical interventions for controlling myopia progression.

Experimental designs and methods: Central and peripheral eye length and  choroidal thickness of will be measured in response to optical interventions, and results will help develop the model. Once the model is validated, novel myopia control agents could be tested.

BIOGRAPHY  

Ornella graduated from Bausch and Lomb School of Optometry, India in 2013. She then return to her home country (Cameroon) and joined the teaching team of a training school in Yaounde as an Optometrist Lecturer. She is currently pursuing her PhD at the UNSW School of Optometry and Vision Science and her research area is myopia. 

Education 

2016 -  PhD, UNSW Sydney, Australia

2009 - 2013  Bachelor of Science in Optometry, Bausch & Lomb School of Optometry, India 

 

RECENT PUBLICATIONS 

Journal Articles 

  1. Peripheral eye length measurement techniques: a review.  (https://doi.org/10.1111/cxo.12892
  2. Paper review on Review of myopia management (https://reviewofmm.com/global-variations-and-time-trends-in-the-prevalence-of-childhood-myopia-a-systematic-review-and-quantitative-meta-analysis-implications-for-aetiology-and-early-prevention/) 

 

AWARDS 

The International Society for Contact Lens Research (ISCLR) Student Grant 

The Postgraduate Research Student Support (PRSS) Scholarship, University of New South Wales 

Tuition Fees Scholarship for PhD, University of New South Wales and The Brien Holden Vision Institute 

 

CONFERENCE ATTENDANCE 

The Association for Research in Vision and Ophthalmology (ARVO) 2019

Poster presentation (Effects of short-term imposed optical defocus on central and peripheral eye length, choroidal thickness and accommodative responses in young healthy subjects) 

The International Society for Contact Lens Research (ISCLR) 2019

Paper and Poster presentation (Time of the day and influence of optical defocus on eye length and choroidal thickness) 

 

AFFILIATIONS AND MEMBERSHIPS 

Member, International Society for Contact Lens Research  

Member, Association for Research in Vision and Ophthalmology  

Member, Women in Math and Science Champion team, University of New South Wales 

Cameroon Association of Optometrists