Research Title: An eye model involving short term exposure to optical defocus: central and peripheral eye length and choroidal thickness
Supervisors: Prof Padmaja Sankaridurg and Dr Cathleen Fedtke
Email Address: email@example.com / firstname.lastname@example.org
Linkedin: Ingrid Ornella Mekountchou Koumbo
Over the last few decades, information about onset and progression of myopia has been greatly enhanced by lens compensation experiments. To reduce the burden associated with myopia, various interventions (optical, pharmaceutical and behavioural) to retard the progression of myopia in children have been investigated. Some of these interventions show promise and studies are underway to improve the efficacy obtained from these interventions. However, these interventions require long term and expensive clinical studies and therefore limit the ability to measure the efficacy of various interventions. Previous studies have found choroidal thickness and eye length to change in response to optical defocus and provide a valuable measure to screen for the effect of optical interventions but were mostly confined to central retina. Given that several studies show that the peripheral eye is also involved in onset and progression of myopia, it is of interest to also evaluate the response of the peripheral retina to optical defocus.
To appreciate the efficacy and/or efficiency of a treatment, it would be highly desirable to be able to confidently predict ocular changes after exposure to any optical treatment to treat myopia. In other terms, there is a need for an eye model that reflects the changes that happen in the eye long term. The objective of this thesis is to determine if a model to evaluate ocular response to short term exposure with optical defocus could be developed using the parameters of central and peripheral eye length and choroidal thickness. The experiments include identifying and improving methods to measure central and peripheral eye length and choroidal thickness and to determine repeatability of methods; conducting a provocative test to determine the limits of change of choroidal thickness; imposing short term optical defocus on human eyes and measure central and peripheral eye length and choroidal thickness as well as accommodative response, and studying the influence of time of day on eye length and choroidal thickness response to short term optical defocus.
Ornella graduated from Bausch and Lomb School of Optometry, India in 2013. She then returned to her home country (Cameroon) and joined the teaching team of a training school in Yaounde as an Optometrist Lecturer. She is currently pursuing her PhD at the UNSW School of Optometry and Vision Science and her research area is myopia.
2016 - PhD, UNSW Sydney, Australia
2009 - 2013 Bachelor of Science in Optometry, Bausch & Lomb School of Optometry, India
Reports and Book Chapters
Conference Abstract- Effects of short-term imposed optical defocus on central and peripheral eye length, choroidal thickness and accommodative responses in young healthy subjects.
Paper review on Review of myopia management (https://reviewofmm.com/global-variations-and-time-trends-in-the-prevalence-of-childhood-myopia-a-systematic-review-and-quantitative-meta-analysis-implications-for-aetiology-and-early-prevention/)
The International Society for Contact Lens Research (ISCLR) Student Grant
The Postgraduate Research Student Support (PRSS) Scholarship, University of New South Wales
Tuition Fees Scholarship for PhD, University of New South Wales and The Brien Holden Vision Institute
The Association for Research in Vision and Ophthalmology (ARVO) 2019- Poster presentation (Effects of short-term imposed optical defocus on central and peripheral eye length, choroidal thickness and accommodative responses in young healthy subjects)
The International Society for Contact Lens Research (ISCLR) 2019- Paper and Poster presentation (Time of the day and influence of optical defocus on eye length and choroidal thickness)
AFFILIATIONS AND MEMBERSHIPS
Member, International Society for Contact Lens Research
Member, Association for Research in Vision and Ophthalmology
Member, Women in Maths and Science Champion team, University of New South Wales
Cameroon Association of Optometrists