Research Title: In-vivo Corneal Confocal Microscopy and Tear Neuropeptides in Chemotherapy-Induced Peripheral Neuropathy
Cancer is one of the leading causes of death worldwide. While survival rates have improved, many patients suffer from long-lasting side effects. Nerve damage in the hands and feet from chemotherapy treatment, known as chemotherapy-induced peripheral neuropathy (CIPN) is a common, debilitating condition. Patients can feel pain, numbness or tingling lasting for years even after chemotherapy has stopped. Unfortunately, there is no treatment and no reliable way to catch this nerve damage.
My research investigates whether in-vivo corneal confocal microscopy can be used as to diagnose CIPN rapidly, reliably and non-invasively. The cornea is the most sensitive and has the highest number of nerves than any part of the human body. It forms the frontmost part of the eye, so it is easily accessible for quick eye scans. I am also researching how tears could be an indicator of the health of a patient, similar to a blood test but without the needles.
TOP 3 PUBLICATIONS
- Chiang JCB, Goldstein D, Park SB, Krishnan AV, Markoulli M. Corneal nerve changes following treatment with neurotoxic anticancer drugs. Ocul Surf. 2021;21:221-37.
- Chiang JCB, Goldstein D, Trinh T, et al. A cross-sectional study of sub-basal corneal nerve reduction following neurotoxic chemotherapy. Transl Vis Sci Technol. 2021;10(1):24-24.
- Chiang JCB, Goldstein D, Trinh T, et al. A cross-sectional study of ocular surface discomfort and corneal nerve dysfunction after paclitaxel treatment for cancer. Sci Rep. 2021;11(1):1786.
Jeremy is an alumnus of UNSW Sydney who graduated with the University Medal from the School of Optometry and Vision Science. He has worked as a clinical optometrist in both private and corporate practice, and is very passionate about advanced multimodal ocular imaging as well as collaborative multidisciplinary patient care. He is also a keen educator and clinical supervisor for optometry, medical and research students. Jeremy is an avid traveler who loves the outdoors and camping. He values sharing research and effective science communication with the general public. Above all he ensures he has a good work-life balance, and enjoys his time with his partner, family and friends
2019 - Current PhD Candidate, School of Optometry and Vision Science, UNSW Sydney
2012 - 2016 Bachelor of Optometry (Honours)/Bachelor of Science, School of Optometry and Vision Science, UNSW Sydney
- NSW Branch Scholarship for Australian Public Health Conference 2020, Public Health Association of Australia, 2020.
- Best presentation in the Annual Progress Review Conference for Higher Degree Research Students, School of Optometry and Vision Science, UNSW Sydney, 2020.
- Best presentation in Optometry and Vision Science, UNSW Science 1 Minute Thesis Competition and Postgraduate Showcase, UNSW Sydney, 2020.
- The Association for Research in Vision and Ophthalmology (ARVO) International Travel Grant, ARVO Baltimore, 2020.
- Australian Government Research Training Program Scholarship (RTP), UNSW Sydney, 2019.
- The University Medal in Optometry and Vision Science, UNSW Sydney, 2017.
AFFILIATIONS AND MEMBERSHIPS
- Young Investigator, International Society of Eye Research (ISER)
- Student Member of Australasian Association for Academic Primary Care (AAAPC)
- Member of Public Health Association of Australia (PHAA)
- Member-In-Training, The Association for Research in Vision and Ophthalmology (ARVO)
- Student Member of American Academy of Optometry (AAOPT)
- Member of Optometry Australia (OA)
- Member of Cornea and Contact Lens Society of Australia (CCLSA)
- Member of the Tear Film and Ocular Surface Society (TFOS)