Minh Phan

Postdoctoral Research Fellow
Postdoctoral Fellow

Minh Phan has joined School of Optometry and Vision Science (SOVS) as a Posdoctoral Research Fellow since November 2019. She undertook her PhD in Food Science and Technology at UNSW School of Chemical Engineering under the prestigious Endeavour Postgraduate Scholarship. During her PhD, she used a human colorectal adenocarcinoma cell line (Caco-2 cells) to evaluate changes in cellular biological effects and cellular uptake of phytochemicals as a result of food co-digestion. She tested antioxidant and anti-inflammatory activities of different phytochemical combinations for synergistic effects using both chemical and cellular models, and successfully developed LC-MS/MS methods for the measurement of different bioactive compounds extracted from plant-based materials and cell culture. She had published 6 articles during her PhD candidature in high impact peer-reviewed journals. 

Minh will apply her expertise in human cell culture and analytical chemistry for delivering studies to investigate the effects of sex hormones including oestrogens and androgens on the tear film and ocular surface using human meibomian gland epithelial cell (HMGEC) line. She is working with other senior SOVS researchers to establish cell culture conditions for differentiation of HMGEC, and to develop LC-MS/MS methods for quantification of sex steroids and lipids produced by HMGEC cells.



Journal articles
Phan MAT; Bucknall MP; Arcot J, 2019, 'Co-ingestion of red cabbage with cherry tomato enhances digestive bioaccessibility of anthocyanins but decreases carotenoid bioaccessibility after simulated in vitro gastro-intestinal digestion', Food Chemistry, vol. 298, pp. 125040, http://dx.doi.org/10.1016/j.foodchem.2019.125040
Phan MAT; Bucknall MP; Arcot J, 2019, 'Effects on intestinal cellular bioaccessibility of carotenoids and cellular biological activity as a consequence of co-ingestion of anthocyanin- and carotenoid-rich vegetables', Food Chemistry, vol. 286, pp. 678 - 685, http://dx.doi.org/10.1016/j.foodchem.2019.02.046
Phan MAT; Bucknall MP; Arcot J, 2019, 'Interferences of anthocyanins with the uptake of lycopene in Caco-2 cells, and their interactive effects on anti-oxidation and anti-inflammation in vitro and ex vivo', Food Chemistry, vol. 276, pp. 402 - 409, http://dx.doi.org/10.1016/j.foodchem.2018.10.012
Phan MAT; Bucknall M; Arcot J, 2018, 'Effect of different anthocyanidin glucosides on lutein uptake by Caco-2 cells, and their combined activities on anti-oxidation and anti-inflammation in vitro and ex vivo', Molecules, vol. 23, http://dx.doi.org/10.3390/molecules23082035
Phan MAT; Bucknall M; Arcot J, 2018, 'Interactive effects of β-carotene and anthocyanins on cellular uptake, antioxidant activity and anti-inflammatory activity in vitro and ex vivo', Journal of Functional Foods, vol. 45, pp. 129 - 137, http://dx.doi.org/10.1016/j.jff.2018.03.021
Phan MAT; Paterson J; Bucknall M; Arcot J, 2018, 'Interactions between phytochemicals from fruits and vegetables: Effects on bioactivities and bioavailability', Critical Reviews in Food Science and Nutrition, vol. 58, pp. 1310 - 1329, http://dx.doi.org/10.1080/10408398.2016.1254595
Phan MAT; Wang J; Tang J; Lee YZ; Ng K, 2013, 'Evaluation of α-glucosidase inhibition potential of some flavonoids from Epimedium brevicornum', LWT - Food Science and Technology, vol. 53, pp. 492 - 498, http://dx.doi.org/10.1016/j.lwt.2013.04.002