Jerome Ozkan

Lecturer

About me:

Working with the School of Optometry and Vision Science, School of Biological, Earth and Environmental Sciences, Department of Ophthalmology and Ramaciotti Centre for Genomics (UNSW), my current research is looking at the microbial community characteristics in terms of identity, complexity and biogeography, of the conjunctiva and eyelid using both traditional microbial culture and culture-independent DNA analysis (sequencing of the 16S ribosomal RNA gene) to determine what constitutes the core and transient microbiome of the eye and how microbial communities change over time. This research will help in understanding the microbe-host interactions that take place in the eye and whether this influences the aetiology of ocular conditions such as dry eye, blepharitis and corneal infections. These findings will provide directions for further study into alterations inflicted on the ocular microbial profile through prolonged prophylactic antibiotic therapy (e.g. due to cataract surgery) and preserved medications in chronic disease (e.g. glaucoma).

My previous research focused on investigating strategies for reducing contact lens-related inflammatory and infectious adverse events during extended wear of silicone hydrogel contact lenses. I have also been extensively involved in the clinical assessment of novel antibacterial contact lenses including lenses coated/impregnated with silver, selenium, fimbrolide and melimine.

 

EDUCATION

PhD (UNSW, 2015)

BOptom Hons (UNSW, 1990)

 

RESEARCH

  • Determine what constitutes the core and transient microbiome of the eye and how microbial communites change over the eye's microhabitats and the effect of antibiotic therapy on the ocular microbiota.
  • Development of strategies to reduce contact lens contamination and therefore reduced inflammatory/infectious ocular adverse events
  • Assessing the efficacy of contact lenses with novel antimicrobial surfaces
  • Effect of contact lens material and design on conjunctival morphology
  • Efficacy of ocular lubricants on patients with dry eye disease

 

TEACHING

Visiting Lecturer (2016)

OPTM4251 Ocular Therapeutics 4

 

Associate Lecturer (2015)

OPTM3131 Ocular Disease 3 

OPTM4251 Ocular Therapeutics 4

 

Tutor (2014)

OPTM3131 & OPTM3231 Ocular Disease 3

OPTM4151 & OPTM4251 Ocular Therapeutics 4

 

Professional affiliations and service positions

Association for Research in Vision and Ophthalmology (ARVO)

International Society for Contact Lens Research (ISCLR)

International Ocular Inflammation Society (IOIS)

Optometry Australia (OA)

 

 

AWARDS & ACHIEVEMENTS

National Health & Medical Research Council (NHMRC) Early Career Fellowship - Peter Doherty Australian Biomedical Fellowship

The Brian Kirby Prize for Research Excellence in Optometry, University of New South Wales, 2016

The Vision Care Institute Student Travel Fellowship, American Academy of Optometry, 2014, Denver, USA

Teaching Fellowship Award, School of Optometry and Vision Science, University of New South Wales, 2014

PhD Scholarship, Brien Holden Vision Institute, 2014

PhD Scholarship, School of Optometry and Vision Science, University of New South Wales, 2014

Student Travel Grant, 17th Scientific Meeting of the International Society of Contact Lens Research (ISCLR) Travel Award, 2013, Kyoto, Japan

Student Travel Grant, 16th Scientific Meeting of the International Society of Contact Lens Research (ISCLR) Travel Award, 2011, Napa, California 

 

Research Groups

Research Topics

  • Contact lens related infection: epidemiology, microbiology and microbial pathogenesis, resistance to antimicrobials
  • Dry eye: contact lens wear, innervation and symptoms, sex hormones

Publications

Conference Papers
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Ozkan J; Coroneo M; Thomas T; Willcox M, 2019, 'Biogeography of the human ocular microbiota', in Biogeography of the human ocular microbiota, Kaohsiung, Taiwan, presented at International Ocular Inflammation Society, Kaohsiung, Taiwan, 13 November 2019 - 16 November 2019
2019
Ozkan J; Willcox M; Wemheuer B; Wilcsek G; Coroneo M; Thomas T, 2018, 'The biogeography of the human ocular microbiota', in The biogeography of the human eye microbiota, European Molecular Biology Organisation/European Molecular Biology Laboratory Symposia - The Human Microbiome, Heidelberg, Germany, presented at European Molecular Biology Organisation/European Molecular Biology Laboratory Symposia - The Human Microbiome, Heidelberg, Germany, 16 September 2018 - 19 September 2018, http://dx.doi.org/10.1016/j.jtos.2018.11.005
2018
Ozkan J, 2018, 'Genetics of the ocular microbiota', in Assessing the biogeography of the ocular microbiota, Australia/New Zealand Cornea and Eye Bank meeting, Sydney, Australia, presented at Australia/New Zealand Cornea and Eye Bank meeting, Sydney, Australia, 23 February 2018 - 24 February 2018
2018
Ozkan J; Diez-Vives C; Nielsen S; Thomas T; Coroneo M; Willcox M, 2017, 'The Temporal Stability and the Ocular Surface Microbiome', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Baltimore, Maryland, USA, presented at the Association for Research in Vision and Ophthalmology, Baltimore, Maryland, USA, 07 May 2017 - 11 May 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432176306051&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2017
Willcox ; Dutta D; Chen R; Ho KITTY; Ozkan J; Cole N; Zhu H; Kumar NARESH, 2017, 'Human clinical testing of antimicrobial contact lenses.', in Human clinical testing of antimicrobial contact lenses., International Conference on Antimicrobial Research, Madrid, Spain, presented at International Conference on Antimicrobial Research, Madrid, Spain, 01 October 2017 - 03 October 2017
2017
Ozkan J; Lazon de la Jara P; Rathi V; Holden B; Willcox M, 2015, 'Retrospective Analysis of Adverse Event Incidence between Different Proof-of-Principle Interventions Designed to Minimise Lens Contamination during 30-Days Continuous Wear', in Retrospective Analysis of Adverse Event Incidence between Different Proof-of-Principle Interventions Designed to Minimise Lens Contamination during 30-Days Continuous Wear, 18th Scientific Meeting of the International Society for Contact Lens Research, Budapest, Hungary, presented at 18th Scientific Meeting of the International Society for Contact Lens Research, Budapest, Hungary, 23 August 2015 - 28 August 2015
2015
Ozkan J; Bakaraju R; Fedtke C; Chung J; Ehrmann K; Ho A; Holden B, 2013, 'Short-term adaptation of accommodative lag, facility and phoria in myopes fitted with multifocal contact lenses', Association for Research in Vision and Ophthalmology, Seattle, Washington, USA, presented at Association for Research in Vision and Ophthalmology, Seattle, Washington, USA, 05 - 09 May 2013
2013
Ozkan J; Bakaraju R; Fedtke C; Chung J; Ehrmann K; Ho A; Holden B, 2013, 'Short-term adaptation of accommodative lag, facility and phoria in myopes fitted with multifocal contact lenses', Seattle, Washington, USA, presented at Association for Research in Vision and Ophthalmology, Seattle, Washington, USA, 05 May 2013 - 09 May 2013
2013
Ozkan J; Lazon de la Jara P; Naduvilath T; Holden B, 2012, 'Retrospective analysis of differences in physiological response and clinical performance of lenses between Asian and Caucasian contact lens wearers', in Retrospective analysis of differences in physiological response and clinical performance of lenses between Asian and Caucasian contact lens wearers, American Academy of Optometry, Phoenix, USA, presented at American Academy of Optometry, Phoenix, USA, 24 October 2012 - 27 October 2012
2012
Ozkan J; Lazon de la Jara P; Ehrmann K; Lally J; Willcox M, 2011, 'Effect of edge shape and lens geometry changes on conjunctival staining during daily wear.', in Effect of edge shape and lens geometry changes on conjunctival staining during daily wear., British Contact Lens Association, Manchester, UK, presented at British Contact Lens Association, Manchester, UK, 23 May 2011 - 27 May 2011
2011
Zhu H; Kumar A; Ozkan J; Wu D; Masoudi S; Bandara R; Willcox M; Borazjani RN, 2010, 'Bacterial Adhesion to Silicone Hydrogel Lenses', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000442393600134&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2010
Willcox M; Zhu H; Ozkan J; Krishna P, 2010, 'Inflammation during contact lens wear and keratitis: strategies for its control', International Society for Eye Research, Montreal, Canada, presented at International Society for Eye Research, Montreal, Canada, 18 - 21 July 2010
2010
Omali B; Zhu H; Zhau Z; Ozkan J; Xu B; Willcox M; Borazjani R, 2010, 'Effect of cholesterol deposition on bacterial adhesion to contact lenses', Association for Research in Vision and Ophthalmology (ARVO), Fort Lauderdale, Florida, USA, presented at Association for Research in Vision and Ophthalmology (ARVO), Fort Lauderdale, Florida, USA, 02 - 06 May 2010
2010
Ozkan J; Krishna P; McNally J; Willcox M; Holden B, 2009, 'Daily replacement of silicone hydrogel contact lenses during continuous wear as a means of reducing contact lens related ocular adverse events.', in Daily replacement of silicone hydrogel contact lenses during continuous wear as a means of reducing contact lens related ocular adverse events., American Academy of Optometry, Orlando, USA, presented at American Academy of Optometry, Orlando, USA, 27 October 2009 - 30 October 2009
2009
Ozkan J; Papas E, 2008, 'Prospective, cross-over study using dry eye lubricants on symptomatic silicone hydrogel wearers.', in Prospective, cross-over study using dry eye lubricants on symptomatic silicone hydrogel wearers., American Academy of Optometry, San Diego, USA, presented at American Academy of Optometry, San Diego, USA, 22 October 2008 - 25 October 2008
2008
Papas EB; Ozkan J, 2005, 'Effect of dry eye lubricant drops on symptomatic silicone hydrogel wearers', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, presented at 82: E-Abstract 050032 American Academy of Optometry, San Diego, Californa, USA
2005
Ozkan J; Snoxall B; Maher A; Papas EB, 2004, 'Lubricants and their effect on comfort with silicone hydrogel and conventional hydrogel lens wear', in Investigative Ophthalmology and Visual Science, Association of Research Vision Ophthalmology Inc, Rockville, MD, USA, pp. U578 - U578, presented at ARVO 2004: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000223338001511&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2004
Edwards K; Naduvilath T; Tahhan N; Du Toit R; Papas E; Kalliris A; Ozkan J; Sweeney D, 2003, 'Duration of discontinuation from silicone hydrogel extended wear due to adverse responses', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, FT LAUDERDALE, FLORIDA, pp. U306 - U306, presented at Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology, FT LAUDERDALE, FLORIDA, 04 May 2003, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000184607001168&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2003
Journal articles
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Ozkan J; Willcox M; Wemheuer B; Wilcsek G; Coroneo M; Thomas T, 2019, 'Biogeography of the human ocular microbiota', The Ocular Surface, vol. 17, pp. 111 - 118,
2019
Ozkan J; De La Jara PL; Willcox M, 2019, 'Comparative Analysis of Adverse Events from a Series of Proof-of-Principle Extended Wear Studies', Eye and Contact Lens, vol. 45, pp. 88 - 92,
2019
Ozkan J; Willcox MD, 2019, 'The Ocular Microbiome: Molecular Characterisation of a Unique and Low Microbial Environment.', Current eye research, vol. 44, pp. 685 - 694,
2019
Ozkan J; Willcox MD, 2019, 'The Ocular Microbiome: Molecular Characterisation of a Unique and Low Microbial Environment', Current Eye Research, vol. 44, pp. 685 - 694, http://dx.doi.org/10.1080/02713683.2019.1570526
2019
Ozkan J; De La Jara PL; Willcox M, 2019, 'Comparative Analysis of Adverse Events from a Series of Proof-of-Principle Extended Wear Studies', Eye and Contact Lens, vol. 45, pp. 88 - 92, http://dx.doi.org/10.1097/ICL.0000000000000546
2019
Ozkan J; Willcox M; Wemheuer B; Wilcsek G; Coroneo M; Thomas T, 2018, 'Biogeography of the human ocular microbiota', The Ocular Surface, http://dx.doi.org/10.1016/j.jtos.2018.11.005
2018
Ozkan J; Coroneo M; Willcox M; Wemheuer B; Thomas T, 2018, 'Identification and visualization of a distinct microbiome in ocular surface conjunctival tissue', Investigative Ophthalmology and Visual Science, vol. 59, pp. 4268 - 4276, http://dx.doi.org/10.1167/iovs.18-24651
2018
Ozkan J; Nielsen S; Diez-Vives C; Coroneo M; Thomas T; Willcox M, 2017, 'Temporal Stability and Composition of the Ocular Surface Microbiome', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-10494-9
2017
Ozkan J; Rathi VM; De La Jara PL; Naduvilath T; Holden BA; Willcox MDP, 2015, 'Effect of daily contact lens cleaning on ocular adverse events during extended wear', Optometry and Vision Science, vol. 92, pp. 157 - 166, http://dx.doi.org/10.1097/OPX.0000000000000479
2015
Ozkan J; Willcox MDP; Rathi VM; Srikanth D; Zhu H; De La Jara PL; Naduvilath T; Holden BA, 2014, 'Effect of antibiotic drops on adverse events during extended lens wear', Optometry and Vision Science, vol. 91, pp. 13 - 23, http://dx.doi.org/10.1097/OPX.0000000000000123
2014
Dutta D; Ozkan J; Willcox MDP, 2014, 'Biocompatibility of Antimicrobial Melimine Lenses: Rabbit and Human Studies', Optometry & Vision Science, vol. 91, pp. 570 - 581, http://dx.doi.org/10.1097/OPX.0000000000000232
2014
Ozkan J; Ehrmann K; Meadows D; Lally J; Holden BA; De la jara PL, 2013, 'Lens parameter changes under in vitro and ex vivo conditions and their effect on the conjunctiva', Contact Lens and Anterior Eye, vol. 36, pp. 171 - 175, http://dx.doi.org/10.1016/j.clae.2013.01.004
2013
Ozkan J; Zhu H; Gabriel M; Holden BA; Willcox MDP, 2012, 'Effect of prophylactic antibiotic drops on ocular microbiota and physiology during silicone hydrogel lens wear', Optometry and Vision Science, vol. 89, pp. 326 - 335, http://dx.doi.org/10.1097/OPX.0b013e318243280e
2012
Ozkan J; Willcox MD; de La Jara PL; Mandathara PS; Rathi VM; Thomas V; Holden BA, 2012, 'The effect of daily lens replacement during overnight wear on ocular adverse events', Optometry and Vision Science, vol. 89, pp. 1674 - 1681, http://dx.doi.org/10.1097/OPX.0b013e31827731ac
2012
Vijay AK; Zhu H; Ozkan J; Wu D; Masoudi S; Bandara R; Borazjani R; Willcox MD, 2012, 'Bacterial adhesion to unworn and worn silicone hydrogel lenses', Optometry and Vision Science, vol. 89, pp. 1095 - 1106, http://dx.doi.org/10.1097/OPX.0b013e318264f4dc
2012
Omali NB; Zhao Z; Zhong L; Raftery MJ; Zhu H; Ozkan J; Willcox MDP, 2012, 'Quantification of protein deposits on silicone hydrogel materials using stable-isotopic labeling and multiple reaction monitoring', Biofouling, vol. 28, pp. 697 - 709, http://dx.doi.org/10.1080/08927014.2012.702763
2012
Dantam J; Zhu H; Willcox MD; Ozkan J; Naduvilath T; Thomas V; Stapleton FJ, 2012, 'In vivo assessment of antimicrobial efficacy of silver-impregnated contact lens storage cases', Investigative Ophthalmology and Visual Science, vol. 53, pp. 1641 - 1648, http://dx.doi.org/10.1167/iovs.11-8197
2012
Omali N; Zhu H; Zhao Z; Ozkan J; Xu B; Borazjani R; Willcox MD, 2011, 'Effect of cholesterol deposition on bacterial adhesion to contact lenses', Optometry and Vision Science, vol. 88, pp. 950 - 958, http://dx.doi.org/10.1097/OPX.0b013e31821cc683
2011
Willcox MD; Phillips B; Ozkan J; Jalbert I; Meagher L; Gene T; Holden BA; Papas E, 2010, 'Interactions of lens care with silicone hydrogel lenses and effect on comfort', Optometry and Vision Science, vol. 87, pp. 839 - 846, http://dx.doi.org/10.1097/OPX.0b013e3181f3e2fc
2010
Willcox MD; Naduvilath T; Vaddavalli P; Holden BA; Ozkan J; Zhu H, 2010, 'Corneal erosions, bacterial contamination of contact lenses and microbial keratitis', Eye and Contact Lens, vol. 36, pp. 340 - 345, http://dx.doi.org/10.1097/ICL.0b013e3181f57b05
2010
Ozkan J; Mandathara P; Krishna P; Naduvilath T; Willcox MD; Holden BA, 2010, 'Risk factors for corneal inflammatory and mechanical events with extended wear silicone hydrogel contact lenses', Optometry and Vision Science, vol. 87, pp. 847 - 853, http://dx.doi.org/10.1097/OPX.0b013e3181f6f97d
2010
Diec J; Carnt N; Tilia D; Evans VE; Rao V; Ozkan J; Holden BA, 2009, 'Prompt diagnosis and treatment of microbial keratitis in a daily wear lens', Optometry and Vision Science, vol. 86, pp. E904 - E907, http://dx.doi.org/10.1097/OPX.0b013e3181ae0084
2009
Stapleton FJ; Ozkan J; Jalbert I; Holden BA; Petsoglou C; McClellan KA, 2009, 'Contact lens-related acanthamoeba keratitis', Optometry and Vision Science, vol. 86, pp. 1196 - 1201, http://dx.doi.org/10.1097/OPX.0b013e3181baae11
2009
Zhu H; Kumar A; Ozkan J; Bandara R; Ding A; Perera I; Steinberg P; Kumar N; Lao W; Griesser SS; Britcher L; Griesser HJ; Willcox MDP, 2008, 'Erratum: Fimbrolide-coated antimicrobial lenses: their in vitro and in vivo effects (Optometry and Vision Science (2008) 85 (292-300)', Optometry and Vision Science, vol. 85, pp. 609, http://dx.doi.org/10.1097/OPX.0b013e318180df0a
2008
Ozkan J; Papas EB, 2008, 'Lubricant effects on low Dk and silicone hydrogel lens comfort', Optometry and Vision Science, vol. 85, pp. 773 - 777, http://dx.doi.org/10.1097/OPX.0b013e3181819f37
2008
Zhu H; Kumar A; Ozkan J; Bandara R; Ding A; Perera I; Steinberg PD; Kumar N; Lao W; Griesser S; Britcher L; Griesser HJ; Willcox MD, 2008, 'Fimbrolide-coated antimicrobial lenses: Their in vitro and in vivo effects', Optometry and Vision Science, vol. 85, pp. 292 - 300, http://dx.doi.org/10.1097/OPX.0b013e31816bea0f
2008
Millar TJ; Papas EB; Ozkan J; Jalbert I; Ball MS, 2003, 'Clinical Appearance and Microscopic Analysis of Mucin Balls Associated with Contact Lens Wear', Cornea, vol. 22, pp. 1 - 5, http://dx.doi.org/10.1097/00003226-200311000-00006
2003